Which plant is also a nephrotoxin in the cholecalciferol toxicosis group along with night-blooming jessamine and oak?

• A. night-blooming jessamine (cestrum)
• B. solanum
• C. oak (quercus)
• D. daylily (hemerocallis)

Answer: (D)

Cholecalciferol toxicosis is vitamin D3–induced poisoning that drives marked hypercalcemia and calcium deposition in soft tissues, including the kidneys, leading to nephrotoxicity. Night-blooming jessamine and oak are well-recognized members of this toxin group because they contain cholecalciferol–related compounds that cause this calcium-mediated kidney damage. In this context, the daylily is the plant among the options that also fits with the same nephrotoxic pattern, making it the best match. Animals poisoned this way often develop vomiting, anorexia, polyuria/polydipsia, dehydration, and, eventually, kidney failure; diagnosis relies on history and labs showing elevated calcium and renal parameters, with treatment focusing on decontamination when possible and aggressive supportive care to promote calciuresis, sometimes supplemented with agents to counteract hypercalcemia.