Which animals are more susceptible to aflatoxicosis?

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Multiple Choice

Which animals are more susceptible to aflatoxicosis?

Explanation:
Susceptibility to aflatoxins depends on how the toxin is absorbed and processed by the body. Monogastric animals, like swine and poultry, take up aflatoxin B1 quickly from the gut, and their detoxification systems aren’t as effective at preventing the liver from converting it into the highly reactive aflatoxin epoxide. This epoxide damages liver cells, impairs immune function, and reduces growth, making these animals particularly vulnerable. In ruminants, the rumen microbes can degrade some aflatoxin B1 before it reaches the bloodstream, reducing the effective dose and toxicity, so they are less susceptible than monogastrics. Fish show variable responses depending on species and exposure, but the pattern of higher risk is most consistent in monogastric terrestrial animals like swine and poultry. Hence, monogastric animals are more susceptible to aflatoxicosis.

Susceptibility to aflatoxins depends on how the toxin is absorbed and processed by the body. Monogastric animals, like swine and poultry, take up aflatoxin B1 quickly from the gut, and their detoxification systems aren’t as effective at preventing the liver from converting it into the highly reactive aflatoxin epoxide. This epoxide damages liver cells, impairs immune function, and reduces growth, making these animals particularly vulnerable. In ruminants, the rumen microbes can degrade some aflatoxin B1 before it reaches the bloodstream, reducing the effective dose and toxicity, so they are less susceptible than monogastrics. Fish show variable responses depending on species and exposure, but the pattern of higher risk is most consistent in monogastric terrestrial animals like swine and poultry. Hence, monogastric animals are more susceptible to aflatoxicosis.

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