M1 is a metabolite of which aflatoxin and found in milk?

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Get ready for the ACVPM Toxicology Exam with our comprehensive quiz. Enhance your knowledge with multiple-choice questions and detailed explanations. Prepare effectively for your certification exam!

Multiple Choice

M1 is a metabolite of which aflatoxin and found in milk?

Explanation:
Aflatoxin M1 in milk comes specifically from exposure to aflatoxin B1. When animals ingest B1, the liver metabolizes it and one of the detoxified products is aflatoxin M1, which is more water‑soluble and excreted in milk. This is why milk can contain M1 after cows consume feed contaminated with B1. The other aflatoxins (B2, G1, G2) have different metabolic pathways and do not produce M1 as their characteristic milk metabolite. So the presence of M1 in milk points to aflatoxin B1 exposure.

Aflatoxin M1 in milk comes specifically from exposure to aflatoxin B1. When animals ingest B1, the liver metabolizes it and one of the detoxified products is aflatoxin M1, which is more water‑soluble and excreted in milk. This is why milk can contain M1 after cows consume feed contaminated with B1. The other aflatoxins (B2, G1, G2) have different metabolic pathways and do not produce M1 as their characteristic milk metabolite. So the presence of M1 in milk points to aflatoxin B1 exposure.

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